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General description
LiChrospher® RP-18 is a reliable and versatile traditionally produced spherical silica gel carrier with C-18 reversed phase properties. It is well suited for the separation of neutral, acidic and weak basic compounds.
Application
Fast Determination of a Novel Iron Chelate Prototype Used as a Fertilizer by Liquid Chromatography Coupled to a Diode Array Detector.: This study explores the use of LiChrospher® 100 RP-18 (5 µm) for the rapid analysis of a new iron chelate fertilizer, showcasing its effectiveness in agricultural applications (Valverde et al., 2021).
Application of Chemometric Approach for Development and Validation of High-Performance Liquid Chromatography Method for Estimation of Ropinirole Hydrochloride.: The research utilizes LiChrospher® 100 RP-18 (5 µm) for the quantification of ropinirole in pharmaceutical formulations, highlighting its precision and robustness (Fatima et al., 2019).
Quantification of Alprenolol and Propranolol in Human Plasma Using a Two-Dimensional Liquid Chromatography (2D-LC).: This paper demonstrates the application of LiChrospher® 100 RP-18 (5 µm) in clinical settings for the analysis of beta-blockers in plasma, indicating its utility in pharmacokinetics (Gonçalves et al., 2017).
Ultrasound-Assisted Surfactant-Enhanced Emulsification Micro-Extraction Followed by HPLC for Determination of Preservatives in Water, Beverages, and Personal Care Products.: The study highlights the use of LiChrospher® 100 RP-18 (5 µm) for environmental and quality control analyses, demonstrating its versatility in various matrices (Jan-E et al., 2017).
Development and Validation of Stability-Indicating HPLC Method for Determination of Cefpirome Sulfate.: This research focuses on the stability testing of cefpirome using LiChrospher® 100 RP-18 (5 µm), emphasizing its reliability for pharmaceutical quality control (Zalewski et al., 2014).
Analysis Note
Application test: passes test
Pressure: ≤ 35 bar
Theoretical Plates (N/m) (Toluene): ≥ 60000
stability testing (performance): passes test
separation factor (Acetophenone/Phenol, selectivity test): 2.05 – 2.25
separation factor (Acetophenone/Cinnamic acid, selectivity test): 1.24 – 1.37
capacity factor (Toluene): 13.0 – 18.0
Legal Information
LiChrospher is a registered trademark of Merck KGaA, Darmstadt, Germany
