Application
High-performance liquid chromatographic determination of the antifungal drug fluconazole in plasma and saliva of human immunodeficiency virus-infected patients.: This study highlights a method using RP-18 for the determination of fluconazole, demonstrating the column′s effectiveness in bioanalytical contexts (Beijnen JH et al., 1995).
Determination of serum aluminium using an ion-pair reversed-phase high-performance liquid chromatographic-fluorimetric system with lumogallion.: This research utilizes RP-18 to analyze serum aluminum, showcasing its utility in trace metal analysis in clinical samples (Ong CN et al., 1995).
A radiochemical high-performance liquid chromatographic method for the analysis of 2-fluoro-2-deoxy-D-glucose-derived metabolites in human chondrocytes.: The method developed employs RP-18, underscoring its role in the radiochemical analysis of complex biological matrices (Greiling H et al., 1993).
Systematic approach to the determination of cephalosporins in biological fluids by reversed-phase liquid chromatography.: This study demonstrates the application of RP-18 in the pharmacokinetic analysis of cephalosporins, further proving the column′s broad applicability in pharmaceutical analyses (Juge F et al., 1983).
Simultaneous determination of 3,4-dihydroxyphenylalanine, 5-hydroxytryptophan, dopamine, 4-hydroxy-3-methoxyphenylalanine, norepinephrine, 3,4-dihydroxyphenylacetic acid, homovanillic acid, serotonin, and 5-hydroxyindoleacetic acid in rat cerebrospinal fluid and brain by high-performance liquid chromatography with electrochemical detection.: This research uses RP-18 to simultaneously quantify multiple neurotransmitters, highlighting its sensitivity and specificity for neurochemical analysis (Huot S et al., 1982).
Analysis Note
Theoretical Plates (N/m) (Toluene): ≥ 25000
stability testing (performance): passes test
particle size (Malvern) (d10): 8.7 – 10.0 µm
particle size (Malvern) (d50): 12.0 – 14.0 µm
particle size (Malvern) (d90): 17.5 – 20.5 µm
Legal Information
LiChrosorb is a registered trademark of Merck KGaA, Darmstadt, Germany

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