Spectinomycin dihydrochloride pentahydrate

Application
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Spectinomycin dihydrochloride pentahydrate may be used as a reference standard for the determination of spectinomycin in bovine milk samples by liquid chromatography with electrochemical detection.[1] Spectinomycin is an aminocyclitol antibiotic derived from Streptomyces spectabilis. It has been shown to have a wide variety of uses, including treating acute gonorrheal urethritis and cervictis, to mark cell layers to monitor cell fate during leaf development, as a selection marker in plant related transformation systems for plant cells containing the marker gene Spcr, to study respiratory tract infections of cattle caused by Pasteurella multocida and Mannheimia haemolytica, and to generate plants deficient for the plastid-encoded RNA polymerase on MS-agar media. Spectinomycin also has use in amplification of low copy number plasmid carrying replicons. It is recommended for use in cell culture applications at 7.5-20 mg/L.
Disclaimer
Solutions can be stored at 2-8°C for several weeks or at -20°C for more extended periods.
General description
Chemical structure: aminoglycoside
Preparation Note
Stock solutions should be prepared at 10 mg/mL in water and filter sterilized.
Legal Information
VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany