Tiếng ViệtGeneral description
Chemical structure: amino acid derivatives
Application
For use in hybridoma cell culture applications as a myeloma selection agent. Used to study inhibition of formylglycinamide ribonucleotide amidotransferase and PRPP amidotransferase.
Biochem/physiol Actions
Azaserine is an antibiotic, generated by Streptomyces fragilis.[1] It is considered as a potential mutation inducing agent.[2] It is known to promote pancreatic cancer and induces adenoma and carcinoma in vivo and in vitro. Azaserine also stimulates kidney and liver tumors in rats.[1]
Preparation Note
Reconstitute contents of vial with 10 mL sterile cell culture medium. Stock solution is sufficient to prepare 500 mL medium. Final working concentration: 5.7 μM azaserine.
Legal Information
Hybri-Max is a trademark of Sigma-Aldrich Co. LLC
Azaserine
Hybri-Max™, γ-irradiated, 50x, lyophilized powder, BioXtra, suitable for hybridoma
Code: A1164
- Manufacturer: Merck
- Trademark: Sigma-Aldrich
- Hãng sản xuất: Merck
| Hãng sản xuất |
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