(−)-Scopolamine hydrochloride

Analysis Note
purity : ≥96.0% (HPLC)
Application
(−)-Scopolamine hydrochloride may be used as a precursor for the preparation of scopolamine, employed as an analytical standard for the quantification of the scopolamine in the floral nectar and plant organs of Datura species[1][2] using various chromatographic techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Biochem/physiol Actions
Competitive nonselective muscarinic acetylcholine antagonist.
Competitive nonselective muscarinic acetylcholine antagonist. Scopolamine-induced amnesia in laboratory animals is a commonly-used model of memory deficit.
General description
(−)-Scopolamine hydrochloride belongs to the class of naturally occurring tropane alkaloids of medicinal interest,[2] found in several members of the Solanaceae family, commonly Atropa belladonna and representatives of the genera Datura and Duboisia.[1]

For the analysis of the phytotoxins.
Preparation Note
Dried down, concentration of (S)-(-)-Scopolamine (free base) after reconstitution ~100μg/mL