8-Methoxypsoralen

analytical standard
Code:M35011 g- M3501-1G
5 g- M3501-5G

Manufacturer: Merck
Trademark: Supelco

Hãng sản xuất: Merck

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Category: Standard Chemical Brand: Supelco

Description
Additional information

Application
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Biochem/physiol Actions
8-methoxypsoralen (8-MOP) plus ultraviolet A (UVA) irradiation induces monoadducts and interstrand cross-links in DNA and therefore can be used to study DNA repair and recombination mechanisms. Cultured normal human melanocytes treated with 8-methoxypsoralen and irradiated with ultraviolet A (UVA) formed 8-methoxypsoralen-phospholipid photoadducts that could be substituted for diacylglycerol to activate protein kinase C in a cell-free system. 8-MOP is an inactivator of purified reconstituted cytochrome P450. It also inhibits substance P-induced histamine release from substance P-activated rat peritoneal mast cells by suppressing the rise in [Ca2+].
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Hãng sản xuất	Merck

8-Methoxypsoralen

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