Flunixin

Application
Flunixin may be used as a reference standard for the determination of NSAID drug, flunixin in biological samples[1][2] using high-performance liquid chromatography with diode array detection (HPLC-DAD)[1]/particle beam mass spectrometry (PB-MS)[2]/atmospheric pressure ionization mass spectrometry (API-MS)[2] and gas chromatography coupled to mass spectrometry (GC-MS).[1] Flunixin may be used as an analytical reference standard for the determination of flunixin in:
Bovine muscle samples by hydrophilic interaction liquid chromatography-electrospray-tandem mass spectrometry (HILIC-ESI-MS/MS) equipped with selected reaction monitoring (SRM) detection.[3] Animal tissues by dispersive-solid phase extraction (d-SPE) and enhanced matrix removal for lipids (EMR-L), followed by analysis using ultra-high performance liquid chromatography-triple quadrupole or quadrupole-time-of-flight (UHPLC-QqQ or UHPLC-Q/TOF) methods in conjunction with ESI-MS/MS operating on multiple reaction monitoring (MRM) mode of detection[4] as well as ESI-LC-MS/MS with SRM detection mode.[5] Porcine muscle samples by ESI-LC-MS/MS with MRM detection mode.[6]

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
General description
Flunixin is a potent nonsteroidal anti-inflammatory drug, primarily used as an anti-inflammatory agent and analgesic for the short-term treatment of moderate pain and inflammation in farm animals.[7][1] It is also effective in inhibiting the synthesis of prostaglandins.[7] Flunixin is classified under the group of non-steroidal anti-inflammatory drugs (NSAIDs).[8] Other Notes
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
Legal Information
VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany