Hexestrol

Application
Hexestrol may be used as a reference standard for the determination of the analyte in biological samples using immunoaffinity extraction and gas chromatography-negative-ion chemical ionization mass spectrometry.[1] Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Biochem/physiol Actions
The carcinogen hexestrol is a nonsteroidal synthetic estrogen. Metabolic activation of hexestrol to its quinone, which reacts with DNA to form analogous depurinating adducts, may be a primary critical event leading to oncogenic mutations and cancer initiation.
General description
Hexestrol is a synthetic nonsteroidal estrogen,[2] which can be used in human medicine as well as a growth promoter in cattle.[1] Other Notes
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
Reduced analogue of diethylstilbestrol.