Isorhamnetin

Application
Isorhamnetin may be used as an analytical reference standard for the determination of isorhamnetin in:
Rat plasma samples by ultra-high performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS) equipped with electrospray ionization (ESI) and multiple reaction monitoring (MRM) mode of detection.[1] Lotus (Nelumbo nucifera) leaves by macroporous resin chromatography combined with HPLC-ESI-MS/MS.[2] Powdered extracts and finished products samples of Ginkgo biloba by HPLC-MS.[3] Human plasma and urine by high-throughput micro solid-phase extraction (μ-SPE), followed by analysis using UHPLC in interface with quadrupole time-of-flight mass spectrometry (Q TOFMS).[4]

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Biochem/physiol Actions
Isorhamnetin inhibits adipogenesis by interfering with differentiation of adipose stem cells, by a mechanism involving stabilization of β-catenin and up-regulating the Wnt signaling pathway.
General description
Isorhamnetin belongs to the flavonoids class of compounds.[5] Other Notes
This compound is commonly found in plants of the genus: ginkgo glycyrrhiza primula
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.