Sulfasalazine

General description
Sulfasalazine (SSZ) belongs to the sulfonamide class of drugs, which can be metabolized into 5-aminosalicylic acid and sulfapyridine.[1] SSZ is obtained as a reaction product of an antibacterial agent (sulfapyridine) and an anti-inflammatory agent (salicylic acid).[2] Chemical structure: sulfonamide
Application
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Sulfasalazine has been used as an analytical standard in clinical studies:
For investigating its therapeutic potential in patients suffering from multiple sclerosis (MS).[3] For studying its role as an antiarthritic agent via inhibition of the cartilage degeneration and pain associated with progression of osteoarthritis in the rat, which is used as the test animal.[4]

It may also be used as an analytical reference standard for the quantification of the analyte in biological samples[5] and aqueous samples[6] using enzyme-linked immunosorbent assay (ELISA)[5] and spectrofluorimetic technique.[6]