General description
The LC-CN phase is often used as a substitute for silica because it offers the advantages of a bonded phase (such as quick equilibration, and less sensitivity to small changes of the water content in the mobile phase). More often, however, the LC-CN column is operated under reversed-phase mobile phase conditions.
Application
Validated Simple HPLC-UV Method for Mycophenolic Acid (MPA) Monitoring in Human Plasma. Internal Standardization: : This study presents a validated HPLC-UV method for monitoring mycophenolic acid in human plasma. The research highlights the necessity and efficiency of internal standardization in achieving accurate measurements. (Kunicki PK et al., 2021).
An Improved HPLC Method for Therapeutic Drug Monitoring of Daunorubicin, Idarubicin, Doxorubicin, Epirubicin, and Their 13-dihydro Metabolites in Human Plasma.: This paper describes an enhanced HPLC method for monitoring therapeutic levels of several chemotherapeutic agents and their metabolites in human plasma, improving the accuracy and reliability of drug monitoring. (Fogli S et al., 1999).
Analysis of Diltiazem and Desacetyldiltiazem in Serum by High-Performance Liquid Chromatography.: This research focuses on an HPLC method for analyzing diltiazem and its primary metabolite in serum, providing a robust tool for clinical pharmacokinetic studies. (Paczkowski D et al., 1995).
High-Performance Liquid Chromatographic Method for the Determination of Eclanamine and Its N-Desmethyl and N,N-Didesmethyl Metabolites in Urine.: The study details a high-performance liquid chromatographic method for determining eclanamine and its metabolites in urine, crucial for pharmacokinetic and toxicological analysis. (Lakings DB et al., 1988).
Other Notes
Discover LiChropur reagents ideal for HPLC or LC-MS analysis
Legal Information
SUPELCOSIL is a trademark of Sigma-Aldrich Co. LLC

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