SPE Cartridges

High-performance SPE cartridges with customizable sorbents and formats for efficient, reliable sample cleanup across a wide range of analytical workflows.

1) Description

Our Solid Phase Extraction (SPE) cartridges are designed for reliable and efficient sample preparation in analytical, environmental, food, and pharmaceutical laboratories. Available in a wide range of bed masses, volumes, and sorbent phases, these cartridges ensure consistent performance for trace-level enrichment, cleanup, and fractionation.

Made from high-purity medical-grade polypropylene, our cartridges are compatible with SPE systems. With customizable configurations including C18, Silica, PSA, NH₂ and more, they provide flexible solutions for diverse sample matrices and analytical methods.

2) Features

▶ Wide Sorbent Selection: Available with C18, Silica, PSA, NH₂, and custom sorbents to suit various analyte chemistries.
▶ Multiple Bed Masses & Volumes: Common formats include 3 mL and 6 mL with bed masses from 200 mg to 1000 mg, adaptable to method requirements.
▶ High Purity Polypropylene Housing: Free from extractables and compatible with most organic solvents.
▶ Excellent Flow Consistency: Uniform packing ensures minimal channeling and optimal retention/recovery rates.
▶ Standard connection Format: Compatible with positive pressure manifolds, vacuum manifolds, and automated SPE instruments.
▶ Secure Packaging: Packed in cleanroom environments; standard pack sizes include 30 or 50 pcs per bag.

 

3) Application

Environmental Analysis: Pre-treatment of water, soil, and wastewater samples for pesticide, PAH, PFAS, and heavy metal testing.

Food Safety Testing: Extraction of veterinary drug residues, mycotoxins, or additives from food matrices.

Pharmaceutical and Biomedical Research: Sample cleanup prior to LC-MS, GC-MS, and HPLC analysis.

Forensic and Clinical Studies: Extraction of drugs, metabolites, or biomarkers from biological fluids.

General Analytical Chemistry: Clean-up and enrichment of trace organic and inorganic analytes.

 

4) Sorbent Selection Guide by Target Compound Type

Target Compound Type Recommended Sorbent(s) Retention Mechanism Typical Sample Types Notes
Non-polar compounds (e.g., pesticides, PAHs, steroids) C18, C8 Hydrophobic interaction Water, serum, urine, plant extracts C18 offers stronger retention than C8; ideal for reversed-phase cleanup
Moderately polar compounds (e.g., phenols, mycotoxins) C18Polymeric RP (e.g., PS-DVB) Hydrophobic + π-π interaction Food, biological fluids Polymeric sorbents are more water-wettable, suitable for polar solvents
Highly polar compounds (e.g., organic acids, catechols) HLBNH₂Diol Hydrogen bonding, dipole-dipole Urine, environmental water HLB retains a broad range; NH₂ useful for weak anion exch. or polar groups
Weak acids (e.g., carboxylic acids, ibuprofen) SAXNH₂ Anion exchange Plasma, pharmaceutical SAX strongly retains acidic groups; pH optimization required
Weak bases (e.g., amines, alkaloids, β-blockers) SCXCMCation-Exchange HLB Cation exchange Plant extract, drugs in serum SCX retains positively charged species; elution with NH₄OH or MeOH
Neutral small molecules (e.g., caffeine, parabens) C18Polymeric RP Hydrophobic Beverage, urine, cosmetics Use mild elution to avoid co-extracting matrix
Aromatic compounds (e.g., benzene derivatives, flavonoids) GCBPhenyl π-π interaction Tea, herbal extracts, soil GCB excels at planar aromatic removal; may adsorb target-test recovery
Sugars, sugar alcohols (e.g., glucose, mannitol) AmineDiol Normal-phase Beverage, fermentation broth Not ideal for reversed-phase; use in NP or HILIC mode
Peptides / proteins (cleanup purpose) C18 (for peptide)GCB (for protein removal) Size exclusion / interaction Serum, plasma Use protein precipitation prior to SPE for better recovery
Hormones & endocrine disruptors (e.g., estradiol, BPA) HLBC18CN Hydrophobic, mixed-mode Environmental water, cosmetics HLB provides broader range capture for trace organics
Pesticides (polar & non-polar) C18GCB/PSA comboQuEChERS + SPE Multi-mode Fruit/vegetables, grains Use multi-layer or tandem SPE for complex matrix cleanup
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