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1) Description
Cellulose acetate (CA) syringe filters with biologically inert, low protein-binding membranes for aqueous and biological samples.
Widely used in analytical and research applications where low extractables and gentle filtration are required.
Uniform microporous structure delivers high flow rates and consistent filtration performance.
Available pore sizes: 0.22 μm and 0.45 μm
Available diameters: 13 mm and 25 mm (larger sizes optional on request)
2)Features
▶ Biologically inert membrane with low nonspecific binding for proteins and biomolecules.
▶ Good thermal stability and chemical compatibility with many aqueous solutions.
▶ Uniform pore structure provides fast flow and efficient particle retention.
▶ Ideal for capturing and culturing microorganisms in water and wastewater analysis.
▶ Compatible with common sterilization methods such as gamma irradiation.
3) Application
◆ Appropriate for bacterial culturing, including E. coli and other microbial tests.
◆ Filtration of buffers, aqueous solutions and biological samples where low protein adsorption is desired.
◆ Clarification of laboratory reagents and sample solutions with high flow requirements.
◆ Suitable for many water and wastewater testing workflows and general lab filtration.
4) How to choose filter size?
0–1 mL sample volume → use 4 mm syringe filters (hold-up volume < 10 μL).
0–10 mL sample volume → use 13 mm syringe filters (hold-up volume < 25 μL).
10–100 mL sample volume → use 25 mm syringe filters (hold-up volume < 100 μL).
10–150 mL sample volume → use 33 mm syringe filters (hold-up volume < 125 μL).
4) FAQ
Q1: What are CA syringe filters mainly used for?
CA syringe filters are mainly used for aqueous solutions, buffers and biological samples, especially when low protein binding and gentle filtration are required.
Q2: Are CA membranes low protein binding?
Yes. Cellulose acetate has low protein adsorption, making it suitable for filtrating protein-containing samples, enzymes and other biomolecules when recovery is important.
Q3: Are CA syringe filters suitable for bacterial or microbial testing?
Yes. CA membranes are commonly used in microbiological applications, including bacterial culturing and filtration of samples prior to plating or analysis.
Q4: Can CA syringe filters be used with organic solvents?
CA is primarily designed for aqueous and some water-miscible solvents.
For strong or highly non-polar organic solvents, PTFE or PVDF is usually preferred.
Q5: What pore size should I choose: 0.22 μm or 0.45 μm for CA?
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- 0.22 μm → for sterilizing filtration and fine particle removal
- 0.45 μm → for routine clarification and filtration of less demanding samples
Q6: Are CA syringe filters suitable for high flow applications?
Yes. The uniform microporous structure of CA membranes supports high flow rates, especially for low-viscosity aqueous samples.
Q7: Are CA syringe filters compatible with sterilization?
Many CA syringe filters are compatible with gamma irradiation or EO sterilization. Check the specific product specification if terminal sterilization is required.
Q8: When should I choose CA instead of PES or PVDF?
Choose CA when you need low protein binding, low extractables and gentle aqueous filtration in routine biological or microbiological workflows, and when your solvents are mainly water-based.
