General description
Platelet factor-4 (PF-4) or chemokine (C-X-C motif) ligand 4 is a CXC chemokine that is expressed in megakaryocytes and stored in the α-granules of platelets.[1] Recombinant human CXCL4 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Biochem/physiol Actions
Platelet factor-4 (PF-4) or chemokine (C-X-C motif) ligand 4 is chemotactic towards neutrophils and monocytes and has been shown to inhibit angiogenesis. This protein associates with heparin and neutralizes it. It also neutralizes various negatively charged proteoglycans.[1][2]
Physical form
0.25 mg/mL in 20 mM Tris-HCl buffer (pH 8.0) containing 0.2 M NaCl, 2 mM DTT and 50% glycerol.
CXCL4 human
recombinant, expressed in E. coli, ≥85% (SDS-PAGE)
Code: SRP6358
- Hãng sản xuất: Merck
- Thương hiệu: Sigma-Aldrich
- Hãng sản xuất: Merck
Kiểm tra giá CXCL4 human

CXCL4 human
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