English
General description
CHIROBIOTIC® R, based on the ristocetin A glycopeptide covalently bonded to high purity silica particles, has shown particular applicability to enantiomers of anionic compounds. Selectivity on CHIROBIOTIC® R strongly correlates to the organic modifier, favoring the alcohol-type mobile phases by a large margin.
Bonded phase: Ristocetin A
Operating pH range: 3.5 – 6.8
Particle diameter: 5, 10 or 16 μm
Pore size: 100 Å
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Chiral Product Literature
Application
Sensitive determination of D-lactic acid and L-lactic acid in urine by high-performance liquid chromatography-tandem mass spectrometry.: This study demonstrates the application of the Astec CHIROBIOTIC R Chiral HPLC Column in the sensitive determination of D-lactic acid and L-lactic acid in urine samples using HPLC-MS/MS. This highlights its utility in clinical and biomedical research for the analysis of chiral molecules in biological fluids (Henry et al., 2012).
New high-performance liquid chromatography method for the determination of (R)-warfarin and (S)-warfarin using chiral separation on a glycopeptide-based stationary phase.: This research utilizes the Astec CHIROBIOTIC R Chiral HPLC Column to develop a method for the chiral separation and determination of warfarin enantiomers. It underscores the column′s application in pharmaceutical analysis, particularly in the study of chiral drug enantiomers (Malakova et al., 2009).
Other Notes
Discover LiChropur reagents ideal for HPLC or LC-MS analysis
Legal Information
Astec is a registered trademark of Merck KGaA, Darmstadt, Germany
CHIROBIOTIC is a registered trademark of Sigma-Aldrich Co. LLC
