English
General description
HPLC cartridge
LiChrospher® RP-18 endcapped is a reliable and versatile traditionally produced spherical silica gel carrier with C-18 endcapped reversed phase properties. It is well suited for the separation of neutral, acidic and weak basic compounds. This sorbent is packed into a LiChroCART 250-4 HPLC cartridge. The connection to the HPLC system is being accomplished by use of the manu-CART NT cartrige holder (1.51486).
Application
Integration of Solid-Phase Extraction and Reversed-Phase Chromatography in Single Protein-Coated Columns for Direct Injection of Bupivacaine in Human Serum: This study highlights the use of the LiChrosorb® RP-8 HPLC column in a novel method integrating solid-phase extraction with reversed-phase chromatography. This approach significantly enhances the efficiency and accuracy of bupivacaine analysis in human serum, underscoring the column′s utility in clinical and pharmaceutical settings. The research demonstrates the column′s high performance in complex sample matrices, making it an invaluable tool for analytical chemists and researchers in drug monitoring and pharmacokinetics (Zarad et al., 2020).
Analysis Note
Pressure: ≤ 40 bar
Theoretical Plates (N/m) (Toluene): ≥ 20000
Symmetry (Toluene): 0.8 – 1.4
Capacity factor (Toluene): 1.5 – 3.0
Legal Information
LICHROCART is a trademark of Merck KGaA, Darmstadt, Germany
LiChrosorb is a registered trademark of Merck KGaA, Darmstadt, Germany
LiChrospher is a registered trademark of Merck KGaA, Darmstadt, Germany
