English
General description
Albumin belongs to the four-member albumin superfamily.[1] It is a major protein in the circulating blood.[2] Albumin has a helical structure with three domains that form a heart-like shape.[1]
Application
Bovine Serum Albumin solution has been used:
to block protein-coated well plates in enzyme-linked immunosorbent assay (ELISA) for immunoreactivity and cross-reactivity studies in the production of monoclonal antibodies (mAbs)[3]
to prepare primary antibody solution for peroxidases staining[4]
as a supplement for in vitro cultivation of Borrelia strains[4]
Biochem/physiol Actions
Bovine serum albumin (BSA) serves as a protein supplement for cell culture media.[5] BSA acts as a transport carrier for drugs, and it is commonly used to study the protein-drug interactions. Furthermore, it is known for its ability to interact with several aromatic and hydrophobic molecules of the bloodstream.[6]
