English
General description
Albumin is present abundantly in serum.[1] Porcine serum albumin (PSA) comprises a flexible C-terminal region compared to other albumins.[2]
Application
Albumin from porcine serum has been used:
as a non-hazardous protein to test its effect on T84 polarized intestinal monolayers and Caco2 polarized intestinal monolayers barrier integrity in trans-Epithelial Electrical Resistance (TEER) assay[3]
to test its effect on the human intestinal epithelial cell lines[4]
to test its interaction with the biodegradable ester-functionalized gemini surfactant 16-E2-16 using ultraviolet (UV)-visible and circular dichroism (CD) spectroscopy measurements[1]
Biochem/physiol Actions
Albumin binds to many blood associated proteins.[2] Porcine serum albumin (PSA) is regarded as a major allergen.[5] PSA is used in the immunosensors, molecularly imprinted nanogels (MIP-NGs) and enzyme-linked immunosorbent assay (ELISA) protein-based detection for assessing contamination, especially in meat products.[2]
Preparation Note
Prepared from albumin (A2764).
