Ovalbumin (323-339) (chicken, Japanese quail)

General description
Ovalbumin (323-339) is an egg white protein surrounded by B-cell epitopes, which are bound by specific IgE antibodies. In addition to this, it also contains CD4+ T cell epitopes.[1] The peptide is a major MHC class II-restricted T-cell epitope of Ovalbumin which is used for studies of immunological allergic responses such as asthma, food allergy and more..
Application
Ovalbumin (323-339) (chicken, Japanese quail) has been used to induce allergic asthma in mice.[2] Biochem/physiol Actions
Ovalbumin (OVA) peptide 323-339 mediates 25–35% of T-cell response to intact OVA in isolated BALB/c mouse. OVA 323-339 has been widely used to determine the characteristics of class II major histocompatibility complex (MHC)-peptide binding and T-cell activation.[1] With the help of two functionally distinct registers ovalbumin (323-339) peptide can bind to histocompatibility complex class II I-A(d) protein.[3] Physical form
Lyophilized from 0.1% aqueous TFA
Other Notes
Lyophilized from 0.1% TFA in H2O