Application
4,4′-Methylene-bis(2-chloroaniline) may be used as an analytical reference standard for the determination of 4,4′-methylene-bis(2-chloroaniline) in:
Urine samples by high performance liquid chromatography (HPLC).[1]
Textile samples by HPLC coupled to tandem mass spectrometry (MS/MS) equipped with multiple reaction monitoring (MRM) mode of detection.[2]
Plastic multilayer food packaging materials by LC-Orbitrap-full scan-high resolution mass spectrometry (HRMS) equipped with electrospray ionization (ESI) source.[3]
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
General description
4,4′-Methylene-bis(2-chloroaniline) is an azo dye metabolite that is deemed toxic to the environment.[4]
This compound is listed in the SVHC (Substances of very high concern) candidate list of ECHA (European Chemicals Agency)
Other Notes
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
Standard for determining aromatic amines released from azo-dyes in commodities[5]

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