General description
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
Aflatoxins are a group of hypertoxic bisdihydrofurano secondary metabolites produced by fungi of the genus Aspergillus, mostly A. flavus, A. Parasiticus, and A. nomius. Aflatoxin M1 is formed upon hydroxylation of one of the major aflatoxins B1 in the milk of dairy animals by the enzyme cytochrome P-450 enzyme.
Application
The CRM was also used as follows:
Aflatoxin M1 analysis of 230 samples of different milk types for enzyme-linked immunosorbent assay (ELISA) based screening followed by confirmation using high-performance liquid chromatography-fluorescence detection (HPLC-FID)
Quantification of aflatoxin M1 in 3198 samples of raw cow milk by liquid chromatography-tandem mass spectrometry (LC-MS/MS)
Other Notes
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Legal Information
TraceCERT is a registered trademark of Merck KGaA, Darmstadt, Germany

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