General description
The most abundant plasma protein in mammals is albumin. It is produced in the liver and transferred as a non-glycosylated protein into the plasma. This multifunctional protein can bind to ligands. [1]
Application
Albumin, Monomer bovine has been used as a:
molecular weight (MW) and polydispersion index (PDI) reference standard for the analysis of hyaluronic acid (HA)-based eye drops[2]
standard in multi-angle light scattering coupled with size exclusion chromatography (SEC-MALS) for calibration[3]
model protein to generate subvisible particles (SVPs) for flow imaging microscopy studies[4]
The binding properties of albumin can be used for a wide range of clinical, pharmaceutical, and biochemical applications.[1]
Biochem/physiol Actions
Albumin is the most important circulatory protein involved in the control of Ca2+ (and Mg2+) levels in mammals.[1]
Preparation Note
Isolated from albumin (A4503) as described for mercaptalbumin in Janatova, J., et al., J. Biol. Chem., 243, 3612 (1968).

English