English
General description
Biotin is also called as B complex vitamin. It is a bicyclic compound, which has a molecular weight of 244.31 Da. Biotin serves as an important cofactor for mammalian carboxylases. It is found within the cells in free and bound pools.[1]
Application
Biotin has been used:
as a M199 media supplement in in vitro culture system[2]
as a component of SATO serum free medium for the isolation of cortical oligodendrocyte precursors (OPCs)[3]
in biochemical precursors culture for de novo fatty acid synthesis[4]
as a component in aggregate culture media[5]
Biochem/physiol Actions
Essential vitamin that is important for amino acid and energy metabolism, and fatty acid synthesis. It is a prosthetic group in four mammalian carboxylase families and facilitates the binding and transfer of carbon dioxide.
