English
General description
Bovine serum albumin (BSA) is bound in a single chain cross-linked with 17 cysteine residues. It comprises three homologous, structurally different domains and two sub-domains each.[1] This globular, α-helical, non-glycosylated protein is produced in the liver.[1]
Application
Bovine Serum Albumin solution has been used:
to study the effects of plasma protein on sulfated glycosaminoglycans (sGAGs)[2]
to histologically evaluate the implanted allogeneic mesenchymal stem cells (MSCs) alginate constructs[3]
as a component of phosphate-buffered saline (PBS) to treat red blood cells (RBC) for sample preparation [4]
Biochem/physiol Actions
Bovine Serum Albumin (BSA) is the most widely used blocking agent in enzyme-linked immunosorbent assay (ELISA).[5] It is also the main constituent of cell culture media.[6] BSA promotes the differentiation of human embryonic stem cells (hESC) differentiation and assists the circulation of drugs, hormones, and fatty acids.[6][1]
