EnglishBiochem/physiol Actions
Granulocyte-macrophage colony stimulating factor (GM-CSF) is a growth and differentiation factor for cells in the granulocyte, macrophage and eosinophil lineage. GM-CSF stimulates colony formation from pluripotential progenitor cells at extremely low concentrations and is an essential survival and proliferative factor for hematopoietic progenitor cells in all divisions up to maturity. It also stimulates growth in some epithelial cells and osteoclasts. GM-CSF is produced by a variety of cell types (monocytes, endothelial cells, T-cells, fibroblasts, mitogen-stimulated B-cells, and LPS-stimulated macrophages). GM-CSF is secreted as a single chain glycoprotein containing 128 amino acids for human with a conserved disulfide bond. Human and murine GM-CSF share approx. 54% sequence homology and do not cross-react in bioactivity.
Physical form
Lyophilized from 10 mM acetic acid plus 250 μg BSA.
Analysis Note
The EC50 activity of mouse GM-CSF is tested in culture using murine FDP-1 cells.
Granulocyte-Macrophage Colony-Stimulating Factor from mouse
≥97% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture
Code: G02825 μg G0282-5UG
50 μg G0282-50UG
- Hãng sản xuất: Merck
- Thương hiệu: Sigma-Aldrich
- Hãng sản xuất: Merck
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Sản phẩm tương tự
D-(+)-Glucose
powder, BioReagent, suitable for cell culture, suitable for insect cell culture, suitable for plant cell culture, ≥99.5%
Code: G7021
- Hãng sản xuất: Merck
- Thương hiệu: Sigma-Aldrich
Fetal Bovine Serum
non-USA origin, sterile-filtered, suitable for cell culture
Code: F7524
- Hãng sản xuất: Merck
- Thương hiệu: Sigma-Aldrich
Dimethyl sulfoxide
≥99.5% (GC), suitable for plant cell culture
Code: D4540
- Hãng sản xuất: Merck
- Thương hiệu: Sigma-Aldrich
CryoStor® cell cryopreservation media
CS10
Code: C2874
- Hãng sản xuất: Merck
- Thương hiệu: Sigma-Aldrich
Millipore® Steriflip® Vacuum Tube Top Filter
pore size 0.22 μm, polyethersulfone membrane, funnel capacity 50 mL, pack of 25 ea
Code: SCGP00525
- Hãng sản xuất: Merck
- Thương hiệu: Millipore
Bovine Serum Albumin
lyophilized powder, ≥96% (agarose gel electrophoresis)
Code: A2153
- Hãng sản xuất: Merck
- Thương hiệu: Sigma-Aldrich
DMEM – high glucose
With sodium Bicarbonate and ʟ-glutamine, without sodium pyruvate, liquid, sterile-filtered, suitable for cell culture
Code: D5796
- Hãng sản xuất: Merck
- Thương hiệu: Sigma-Aldrich
Hyaluronidase from bovine testes
Type I-S, lyophilized powder, 400-1000 units/mg solid
Code: H3506
- Hãng sản xuất: Merck
- Thương hiệu: Sigma-Aldrich
Dulbecco′s Phosphate Buffered Saline
liquid, Modified, without calcium chloride and magnesium chloride, liquid, sterile-filtered, suitable for cell culture
Code: D8537100 mL D8537-100ML
500 mL D8537-500ML
1 L D8537-1L
6 x 500 mL D8537-6X500ML
6 x 1 L D8537-6X1L
24 x 500 mL D8537-24X500ML
- Hãng sản xuất: Merck
- Thương hiệu: Sigma-Aldrich
Trypsin-EDTA solution
0.25%, sterile-filtered, BioReagent, suitable for cell culture, 2.5 g porcine trypsin and 0.2 g EDTA, 4Na per liter of Hanks′ Balanced Salt Solution with phenol red
Code: T4049
- Hãng sản xuất: Merck
- Thương hiệu: Sigma-Aldrich
