EnglishGeneral description
L-ascorbic acid is an unsaturated γ-lactone ring containing an enediol configuration (–COH=COH) attached with a carbonyl group.[1]
Application
For use in cell culture applications as an antioxidant and to regenerate tocopherol.
L-ascorbic acid has been used:
in an osteogenic supplement for the growth of cells[2]
as a component in the differentiation media[3]
in WS-MSCs (Werner syndrome-mesenchymal stem cells) to study rescuing properties of ascorbic acid on aging defects[4]
Biochem/physiol Actions
L-ascorbic acid mainly exhibits antioxidant properties. It protects plants from oxidative stress and mammals from diseases associated with oxidative stress.[5] L-ascorbic acid mainly protects from hydroxyl radicals, superoxide and singlet oxygen. In addition, it also reduces the membrane-linked antioxidant α-tocopherol (oxidised form).[6] L-Ascorbic acid enhances endothelium-dependent vasodilation in various disorders, including diabetes, coronary artery disease, hypertension and chronic heart failure.[1]
Other Notes
2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research
L-Ascorbic acid
powder, suitable for cell culture, γ-irradiated
Code: A4403
- Hãng sản xuất: Merck
- Thương hiệu: Sigma-Aldrich
- Hãng sản xuất: Merck
| Hãng sản xuất |
|---|
Sản phẩm tương tự
Poly-ʟ-Ornithine
synthetic, mol wt 30,000-70,000, liquid, 0.01%, suitable for cell culture
Code: P4957
- Hãng sản xuất: Merck
- Thương hiệu: Sigma-Aldrich
Human Serum
from human male AB plasma, USA origin, sterile-filtered
Code: H4522
- Hãng sản xuất: Merck
- Thương hiệu: Sigma-Aldrich
Millipore® Steriflip® Vacuum Tube Top Filter
pore size 0.22 μm, polyethersulfone membrane, funnel capacity 50 mL, pack of 25 ea
Code: SCGP00525
- Hãng sản xuất: Merck
- Thương hiệu: Millipore
Bovine Serum Albumin
heat shock fraction, protease free, fatty acid free, essentially globulin free, pH 7, ≥98%
Code: A703010 g A7030-10G
50 g A7030-50G
100 g A7030-100G
500 g A7030-500G
1 kg A7030-1KG
5 kg A7030-5KG
- Hãng sản xuất: Merck
- Thương hiệu: Sigma-Aldrich
Mouse Laminin
from Engelbreth-Holm-Swarm murine sarcoma basement membrane, 0.2 μm filtered, liquid, 1-2 mg/mL, suitable for cell culture
Code: L2020
- Hãng sản xuất: Merck
- Thương hiệu: Sigma-Aldrich
Bovine Fibronectin
from bovine plasma, liquid, suitable for cell culture
Code: F1141
- Hãng sản xuất: Merck
- Thương hiệu: Sigma-Aldrich
Dulbecco′s Phosphate Buffered Saline
liquid, Modified, without calcium chloride and magnesium chloride, liquid, sterile-filtered, suitable for cell culture
Code: D8537100 mL D8537-100ML
500 mL D8537-500ML
1 L D8537-1L
6 x 500 mL D8537-6X500ML
6 x 1 L D8537-6X1L
24 x 500 mL D8537-24X500ML
- Hãng sản xuất: Merck
- Thương hiệu: Sigma-Aldrich
Fetal Bovine Serum
USA origin, sterile-filtered, suitable for cell culture, suitable for hybridoma
Code: F2442
- Hãng sản xuất: Merck
- Thương hiệu: Sigma-Aldrich
Poly-ʟ-Lysine Hydrobromide
synthetic, liquid, 0.01%, suitable for cell culture
Code: P4707
- Hãng sản xuất: Merck
- Thương hiệu: Sigma-Aldrich
Trypsin-EDTA solution
0.25%, sterile-filtered, BioReagent, suitable for cell culture, 2.5 g porcine trypsin and 0.2 g EDTA, 4Na per liter of Hanks′ Balanced Salt Solution with phenol red
Code: T4049
- Hãng sản xuất: Merck
- Thương hiệu: Sigma-Aldrich
