General description
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PCASMC were used to investigate the role of c-Jun in smooth muscle proliferation, and to show that c-Jun inhibition abrogates smooth muscle cell growth and intimal thickening after arterial injury (Khachigian, 2002). PCASMC were also used to develop poly (l-lactide-co-caprolactone) nanofibrous scaffold material with potential for tissue engineering (Dong, 2008).
Characterization: positive for smooth muscle cell specific alpha-actin expression.
Application
vascular research, supply of blood to heart muscle
Biochem/physiol Actions
Artery
Preparation Note
2nd passage, >500,000 cells in Porcine Smooth Muscle Cell Basal Medium that contains 10% FBS and 10% DMSO
Can be cultured at least 16 doublings
Please refer to the PCASMC Culture Protocol.
Other Notes
Porcine Smooth Muscle Cell Basal Medium that contains 10% FBS and 10% DMSO

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