Prealbumin from human plasma

General description
Human prealbumin is a product of chromosome 18. It is a serum protein, synthesized primarily in the liver.[1] It is a tetrameric protein with a molecular weight of 55 kDa. Human prealbumin is composed of four identical non-covalently bound monomers of 127 amino acid residues arranged with tetrahedral symmetry.[2] Application
Human prealbumin was used to study reduced transthyretin expression in sera of lung cancer.[3] Prealbumin from human plasma has been used as a positive control in immunoprecipitation[4] as a reference standard in quantitative rocket immunoelectrophoresis for quantification of cerebrospinal fluid.[5] Biochem/physiol Actions
Human prealbumin has been observed in carcinoid tumors.[1] Prealbumin levels are indictors of malnutrition and may be modulated during inflammation.[6] It is regarded as potential marker of protein energy malnutrition (PEM) during chronic kidney failure supported dialysis.[7] Low levels of prealbumin poses high risk to heart failure (HF).[8] Packaging
Package size based on protein content
Physical form
Lyophilized powder containing sodium phosphate and NaCl