Biochem/physiol Actions
PTEN, a tumor suppressor, has been implicated in a large number of human tumors and is conserved from humans to worms. Characterization of PTEN protein showed that it is a phosphatase that acts on proteins and on 3-phosphorylated phosphoinositides, and can therefore modulate signal-transduction pathways that involve lipid second messengers. Recent results indicate that at least part of its role is to regulate the activity of the serine/threonine kinase AKT/PKB, and thus influence cell survival signaling. Recombinant PTEN is purified by proprietary chromatographic techniques.
Physical form
Sterile filtered liquid at 100 μg/ml.
Preparation Note
Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.
PTEN human
Code: SRP4838
- Hãng sản xuất: Merck
- Thương hiệu: Sigma-Aldrich
- Hãng sản xuất: Merck
Kiểm tra giá PTEN human

PTEN human
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