Tobramycin

General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets, have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
Application
It is intended to be used as a USP reference standard in specified quality tests and assays.(1)
Also used to prepare the standard solution for identification and assay of tobramycin and its different dosage forms using thin-layer chromatography (TLC) and liquid chromatography (LC) combined with UV detection at 365 nm respectively, as prescribed in the United States Pharmacopeia (USP) for the following monographs:
Tobramycin
Tobramycin for Injection
Tobramycin Ophthalmic Ointment
Tobramycin Ophthalmic Solution
Tobramycin Injection
Tobramycin Sulfate
Tobramycin and Dexamethasone Ophthalmic Suspension
Tobramycin Inhalation Solution
Tobramycin and Fluorometholone Acetate Ophthalmic Suspension
Tobramycin and Dexamethasone Ophthalmic Ointment
Biochem/physiol Actions
Tobramycin is an aminoglycoside.
Mode of Action: Binds to 70S ribosomal subunit; inhibits translocation; elicits miscoding.
Spectrum of Activity: Gram negative bacteria. Not effective against Enterococci.
Analysis Note
These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind. ​
Other Notes
Sales restrictions may apply.