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General description
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Rat Pulmonary Artery Smooth Muscle Cells (RPASMC) provide a useful in vitro model to study cellular and molecular mechanisms of pulmonary hypertension characterized by hyperproliferation of pulmonary artery smooth muscle cells.Characterization: positive for smooth muscle cell specific alpha-actin expression.
Application
Cell growth, signaling, receptor transactivation and suppression, vascular remodeling.
Biochem/physiol Actions
Artery
Preparation Note
2nd passage, >500,000 cells in Rat Smooth Muscle Cell Basal Medium that contains 10% FBS and 10% DMSO
Can be cultured at least 12 doublings
Please refer to the RPASMC Culture Protocol.
Analysis Note
Each lot was tested for proper morphology, Population Doublings, Negative for HIV, Hepatitis B, Hepatitis C, mycoplasma, bacteria, and fungi.
Other Notes
Rat Smooth Muscle Cell Basal Medium that contains 10% FBS and 10% DMSO
