English
General description
Due to the unstable, hygroscopic nature of the free acid, the calcium salt is employed.
Plants and microorganisms, such as Escherichia coli are the major sources of D-pantothenic acid.[1] It is water soluble[2] and quite stable to heating.[3]
Application
D-Pantothenic acid hemicalcium salt has been used:
as a component of FMX-turbodoma- derived media[2]
as a supplement in DMEM (Dulbecco′s modified eagle media)/F-12 used for cell proliferation[4]
as a supplement in preadipocyte media[5]
Precursor in the biosynthesis of coenzyme A.
Biochem/physiol Actions
Along with coenzyme A (CoA, D-pantothenic acid is a precursor for acyl carrier protein.[1] These are essential cofactors[1] involved in fat, protein and carbohydrate metabolism. It also participates in the formation of acetylcholine neurotransmitter. D-pantothenic acid is considered as a source of nutrition and possesses immune function by mediating antibody formation. The production of cortisone is supported by D-pantothenic acid. It is essential for adrenal gland activity.[3]
