Bovine Serum Albumin

General description
Albumin, Bovine Serum, (BSA) Cohn Fraction is purified by cold ethanol precipitation (Cohn extraction) and by heat treatment to remove lipids and fatty acids. It is a single carbohydrate-free polypeptide and the most abundant (comprising ~60%) of the plasma proteins. BSA regulates the maintenance of osmotic pressure.
BSA belongs to the serum albumin family,[1] comprising three domains with two sub-domains under each. BSA is an α-helical, globular, and non-glycosylated protein with 17-disulfide bonds.[2][1] Biochem/physiol Actions
Bovine serum albumin (BSA) transports sparingly soluble physiological substances, especially long-chain fatty acids, bilirubin, drugs, hormones, and fatty acids.[2] It acts as a blocking agent in enzyme-linked immunosorbent assay (ELISA).[3] BSA is a vital component of the cell culture media and boosts embryonic stem cells (hESC) differentiation.[4] Physical form
30% solution in 0.8% NaCl, 0.1% NaN₃, pH 7.2, sterile-filtered.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)