English
Application
[deamino-Cys1, D-Arg8]-Vasopressin acetate salt hydrate has been used:
in induction of antidiuresis[1]
as agonist of V2-receptor (V2R)[2]
for Von Willebrand factor (VWF) secretion in bleeding diathesis[3]
[deamino-Cys1, D-Arg8]-Vasopressin acetate salt hydrate was used to study the impact of vasopressin on pendrin abundance.[4] E3 ubiquitin (Ub)-protein ligases (E3s) was administered in rat kidney and the changes in protein abundance of the selected E3s in response to [deamino-Cys1, D-Arg8]-Vasopressin acetate salt hydrate was examined.[5]
Biochem/physiol Actions
[deamino-Cys1, D-Arg8]-Vasopressin acetate salt hydrate also known as DDAVP, Desmopressin is a selective and potent vasopressor agent that stabilizes the cardiocirculatory function in normal human as well as in patients suffering from catecholamine-resistant vasodilatory shock.[6] It also stimulate three acid-base transporters and hence increases the capability of the cell to regulate pH.[7]
Preparation Note
[deamino-Cys1, D-Arg8]-Vasopressin acetate salt hydrate dissolves in water at 20 mg/ml to yield a clear, colorless solution.
