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Application
Deoxynivalenol solution has been used as an analytical reference standard for the quantification of the analyte in cornmeal and wheat meal matrices using high-performance liquid chromatography with UV detection (HPLC-UV). It is used as an analytical standard in investigating its toxicity mechanism on human chondrocytes by microarray and bioinformatics analysis.[1]
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
General description
Deoxynivalenol belongs to the group of tetracyclic sesquiterpenoid mycotoxins called trichothecenes[2], produced by Fusarium fungi, naturally occurring in small grains and infected corn.[3]
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Deoxynivalenol is frequently found in cereals and agricultural products including, corn, barley, oats, rye, maize, wheat, malt, bread, beer, etc.[4] It is a mycotoxin and primarily affects the livestock industry by reducing the food intake in farm animals. The effect of DON contamination in cereals and other food samples serves as one of the factors of Kashin-Beck disease, a chronic and endemic osteoarticular disorder.[1]
