English
General description
Earle′s Balanced Salts is a balanced salt solution. It is used as an alternative for conventional simulated body fluids (c-SBF).[1]
Recommended for suspension cultures or whenever cell clumping is a problem.
Application
Earle′s Balanced Salts has been used:
to induce autophagy in mouse embryonic fibroblasts[2]
in the preparation of melanotroph isolation medium[3]
in the preparation of DNAse stock solution[4]
Biochem/physiol Actions
Balanced Salt solution participates in providing cells with water, bulk inorganic ions, and nutrients like carbohydrates essential for normal cell metabolism. It acts as an irrigating, transporting, and diluting fluid to maintain cellular osmotic balance. Balance salt solution helps in maintaining the medium within the physiological pH range (7.2 to 7.6).
