Human Serum Albumin

General description
The gene HSA (human serum albumin) is mapped to human chromosome 4q13.3.[1] The gene encodes a protein of 585 amino acids with a molecular weight of 66.4kDa.[2] HSA is the most abundant protein in the plasma and has many metal-binding sites.[3][4] Application
HSA (human serum albumin) has been used for the development of automated dye-binding method for serum albumin determination using bromcresol purple.[5] It has also been used to study effect of HSA on DNA transfection by lipoplexes.[6] Biochem/physiol Actions
HSA (human serum albumin) mainly works as a carrier for various nutrients, metabolites and xenobiotics. It interacts with plasma zinc and regulates uptake of zinc in cells.[4] HSA plays a crucial role in drug pharmacokinetics.[3] It also controls oncotic pressure and volume of the blood.[7] Mutations in the gene are linked with congenital analbuminemia and familial dysalbuminemic hyperthyroxinemia.[1][8] Physical form
Sterile filtered yellowish liquid.