English
General description
The MultiScreen®-MIC (Migration, Invasion, Chemotaxis) plate is a 96-well disposable device for use in functional assays for screening protein libraries and compound leads for drug discovery. It is designed to support high throughput cell-based functional assays such as migration, invasion, and chemotaxis with suspension and/or adherent cell lines, using a single device. The plates can be used to perform and quantify cell migration or invasion across coated or uncoated membranes in response to a concentration gradient. The MultiScreen-MIC plates are available in several pore sizes to accommodate MIC assays with a variety of cell lines and are intended for single use only.
Application
MultiScreen® Migration Invasion and Chemotaxis Filter Plate, 96 well has been used in the transwell/cellular migration assay using:
interleukin (IL)-4- and IL-12-treated T cells[1]
THP-1 (human acute monocytic leukemia cell line)[2]
in vitro activated, purified and IL-2-maintained galectin-3-deficient (gal3)-/- and gal3+/+ cluster of differentiation 4 (CD4)+ OTII T cells[3]
Legal Information
MULTISCREEN is a registered trademark of Merck KGaA, Darmstadt, Germany
